ACE and hypertensive disorder: Variables having a significant association with development of later adverse events included: history of diagnosis myocarditis and/or pericarditis, history of CHF, history of CEVD, history of HTN, history of DM, history of ACE-Inhibitor (ACE-I), history of beta-blocker, statin, and non-steroidal anti-inflammatory (NSAID) use (Supplemental Table 4).