In the prediction model established with four genes, SLC7A11, NCKAP 1, SLC3A2, and RPN1 [117], in bladder cancer, high SLC7A11 expression was closely associated with cisplatin resistance, and knockdown of NCKAP1, which encodes a component of Nck-associated protein 1 and the WAVE regulatory complex (WAVE), inhibited rectal cancer cell migration [118]. Here, SLC7A11 is linked to rectal cancer.