In addition, the Mykov group reported that MIRA-1 (47) (Fig. 8) [60], a maleimide derivative, and STIMA-1 (48) (Fig. 8) [61], a simple derivative of CP-31398, reactivated DNA binding of mutant p53, restored transcriptional activity of mutant p53 in cells, and induced mutant p53-dependent cell death in human tumor cell lines. The gene discussed is TP53; the disease is neoplasm.