CD30 may also be expressed in a subset of epithelioid angiosarcomas, while the lymphatic marker D2-40 is variably expressed, suggesting focal lymphatic differentiation in the tumor.[1–4,11,12] Positive ERG and CD31 staining, combined with histopathological findings from autopsy tissue, confirmed our final diagnosis. Here, TNFRSF8 is linked to angiosarcoma.