Interestingly we found that, in contrast to our observations with FH, the presence of plasma from convalescent children enhanced the binding of C1-INH to the merozoites, as the MFI of the staining for this molecule was significantly higher when the parasite was incubated with the children plasma samples compared with the adult plasma samples (Fig 4A and 4B). Here, SERPING1 is linked to familial hyperaldosteronism.