To further investigate whether the synapse loss induced by S. aureus infection in adult mice was associated with increased engulfment of synaptic components by microglia, post-synaptic marker Homer1, lysosomal marker CD68, and the microglial marker Iba-1 co-staining of brain sections was conducted on D1, D3, and D7 post-infection. The gene discussed is HOMER1; the disease is infection.