To investigate whether the abnormal behaviors result from S. aureus-induced neuron death in the hippocampus (cognitive/memory impairment) and striatum (motor function) regions, we immunostained the neuronal marker NeuN along with the apoptosis marker Caspase-3 in the hippocampus and striatum three days post-infection (Fig 1F and 1G). This evidence concerns the gene RBFOX3 and infection.