No subgroup was identified that showed a significant association between statin use and IDFS, DRFI nor OS: When stratified by treatment arm within the APHINITY trial, menopausal status, BMI, tumor size, nodal status or hormone receptor status, treatment with statins in general, lipohilic or hydrophilic statins was not associated with survival outcomes. The gene discussed is NR4A1; the disease is neoplasm.