Studies have shown that CCL5, a marker of MP3 shown in the present study, may contribute to the accumulation of CD8 T cells53, 54; however, elevated CCL5 levels are linked to an unfavourable prognosis and hinder the ability of CD8 T cells to eradicate tumours in GC.55, 56, 57, 58. The gene discussed is CD8A; the disease is gastric cancer.