In a rat model of reflux esophagitis (RE), Flos Lonicerae (LF) decreased esophageal and gastric mucosal lesions, lipid peroxidation, and collagen accumulation, and enhanced antioxidant indicators such as SOD, CAT, and GSH just like α-tocopherol [147]. This evidence concerns the gene CAT and gastroesophageal reflux disease.