(16)demonstrated the effective ablation of senescent cells in vitro and in vivo by identifying the urokinase plasminogen activator receptor (uPAR) as a cell-surface protein that is widely induced during senescence using mice and showed that uPAR-specific CAR T cells were effective in ablating senescent cells in vitro and in vivo, and the results of the experiment demonstrated that uPAR-targeted CAR T cells prolonged the survival of lung adenocarcinoma mice treated with senescence-inducing drug combinations. Here, PLAUR is linked to lung adenocarcinoma.