SLC31A1 and non-small cell lung carcinoma: The AUC value of anti-COPT1-IgG for the identification of early stage NSCLC from NC was 0.734 (95% CI: 0.686-0.781, sensitivity=63.8%, specificity=71.7%), which was higher than that for NSCLC with late stage (AUC=0.715, 95% CI: 0.649-0.782, sensitivity=38.2%, specificity=90.6%, Figure 7C, Supplementary Figures 3A, B).