Similar eosinophil subpopulations have been identified in the human pulmonary and nasal polyp tissues through the different expression of CD62L and IL-3R as Siglec-8+CD62L+IL3R- cells for iEOS, and Siglec-8+CD62L-IL3R+ for rEOS (8, 18–20). The gene discussed is SELL; the disease is nasal cavity polyp.