In addition, Li et al. (2023) reported that the inhibition of YAP expression inhibited osteoclast maturation and survival regardless of the overexpression of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1), a substance that promotes osteoclast maturation, effectively protected bone and reduced the degree of osteoporosis in ovariectomized mice. The gene discussed is YAP1; the disease is osteoporosis.