PITX3 and Alzheimer disease: AD GCH deficiency (Segawa’s syndrome) [22,23]AR GCH deficiency [24,25]PTPS deficiency [24,25]SRD deficiency [26-28]DHPR deficiency [24,29]TH deficiency type A [30]TH deficiency type B [30]PITX3 deletion [31]Brain dopamine –serotonin vesicular transport disease [32]