As highlighted by Reference (12), carcinomas and mesenchymal tumors with SWI/SNF dysfunction frequently exhibit a discohesive epithelioid or rhabdoid phenotype, necessitating a targeted immunohistochemical evaluation of INI-1 (SMARCB1) and BRG1 (SMARCA4) during diagnostic workup. The gene discussed is SMARCB1; the disease is mesenchymal cell neoplasm.