Its ability to rapidly optimize clustering, phenotyping, and visualize spatial distributions allowed clear delineation of tumor regions, for instance, distinguishing normoxic areas enriched in E-cadherin/β-catenin-positive cells from hypoxic regions dominated by hypoxia-associated cells, thereby providing data-driven insights into tissue organization and tumor microenvironment heterogeneity. This evidence concerns the gene CDH1 and neoplasm.