AXIN1 and inflammatory bowel disease: Notably, TNF and AXIN1 showed a significant increase in inflamed (1.37 and 0.52 increase in mean NPX, respectively) and non-inflamed IBD (1.17 and 0.6 increase in mean NPX, respectively) compared to non-IBD controls, suggesting that these markers may serve as effective biomarkers for IBD, irrespective of the disease activity status, whether it is active or in remission.