Similar studies were also conducted on asthma patients, according to which blood IgE and eosinophil levels were found to be not reliable to predict airway inflammation, based on eosinophil counts in sputum, bronchoalveolar lavage, and endobronchial biopsy.18, 19Moreover, our study showed that the eosinophil count poorly correlates with the IgE concentration in blood, which also suggested that blood may not be reflective of the inflamed environment in nasal polyps and could be impacted by other physiological activities. The gene discussed is IGHE; the disease is asthma.