INS and type 2 diabetes mellitus: SinceT2D is accompanied by an elevated, chronic inflammation,which worsens the metabolic alterations and promotes the developmentof diabetic complications, molecules with anti-inflammatory propertiesmight work synergistically with insulin-mimetic molecules to improvethe metabolic health of people with T2D.35 The unique composition of SSE, including insulin-mimetic compoundsand anti-inflammatory characteristics, as demonstrated in our previousstudies,14,15,36 provides thisextract its high antidiabetic potency.