Figure 6K presents key ubiquitination-related genes (e.g., UBE2E2, UBE2J2, ATXN3, UBE2I) that were significantly upregulated in high-ubiquitination endothelial cells, emphasizing their potential role in regulating metabolism, signaling, and immune functions, potentially affecting tumor progression and patient prognosis. This evidence concerns the gene ATXN3 and neoplasm.