ELANE and bronchiectasis: Neutrophils secrete lytic enzymes such as neutrophil elastase, myeloperoxidase, which are likely to have an impact in the recurrent airway injury of bronchiectasis.4 Many studies have found a link between the action of neutrophil elastase and proinflammatory cytokine levels that increase in patients with bronchiectasis and correlate with lung functions.5,6