The reverse transcription (RT)-qPCR results demonstrated that LIPUS treatment increased the expression levels of pro-differentiation-related genes (Olig2 and Sox10), as well as a significant up-regulation of myelin-related genes such as PLP, MBP, and MOG in mice with cerebral ischemia (Fig. 5C). The gene discussed is OLIG2; the disease is Cerebral ischemia.