SLC27A5 and cancer: Metabolic enzymes have the ability to regulate gene expression, which can, in turn, affect subsequent gene functions and cancer progression by protein-protein interactions, exerting kinase activity, or protein modifications.28, 29, 30, 31 Solute carrier family 27 member 5 (SLC27A5), also known as FATP5, is a fatty acid transport protein exclusively expressed in the liver and involved in bile acid metabolism.32