Proteomics-based analysis has shown that GSTP1 is overexpressed in cisplatin47 and irinotecan5 resistant gliomas, fluorouracil (5-FU) and cisplatin resistant gastric cancer cells,48 doxorubicin resistant prostate cancer cells,49 and adriamycin resistant breast cancer cells.49 The gene discussed is GSTP1; the disease is Familial prostate cancer.