Among alcoholic individuals, GSTM1 null genetic variant carriers are at an elevated risk of developing alcoholic liver disease,138 while studies indicate that in non-alcoholic fatty liver disease, individuals with the Val/Val genotype of GSTP1 and null genotype of GSTT1/GSTM1 null genotype have a higher susceptibility to the disease.139. This evidence concerns the gene GSTM1 and metabolic dysfunction-associated steatotic liver disease.