CPT2 and neoplasm: However, paradoxically, the expression of CPT2 in OC cells and tumor tissues is significantly lower than non-malignant ovarian cells and paired peritumoral normal tissues, respectively,46 even more, low expression of CPT2 is associated with a worse prognosis, perhaps because of G1/G0 cell cycle arrest and increased apoptosis caused by CPT2 overexpression, inhibiting tumor growth and reduced metastasis in vivo experiments.46