With regard to lymphoma, FAO-related enzymes are commonly high expressed,64 It is shown that mitochondrial trifunctional enzyme subunit alpha (HADHA) is increased in malignant lymphoma tissue,64 while HADHB is also an independent predictor of poor prognosis of diffuse large B cell lymphoma (DLBCL).65 The gene discussed is HADHB; the disease is diffuse large B-cell lymphoma.