PIK3CD and cancer: KEGG pathway analysis indicated that 1,8-CH’s potential benefits in supporting mental well-being could be attributed to its influence on several key pathways, including chemical carcinogenesis, PI3K-AKT signaling, HIF-1 signaling, neutrophil extracellular trap formation, adipocytokine signaling, central carbon metabolism in cancer, NOD-like receptor signaling, and thyroid hormone signaling (Figure 4C).