The whole-genome sequencing results indicated a 5.7-fold increase in HSD11B1 expression in leiomyoma cells treated with DEX compared to vehicle controls, whereas this increase was only 3.3-fold in FKBP5-knockdown cells (Fig. 4A; RNA-seq raw data available in the NCBI GEO repository, accession number GSE292403 (20)). Here, HSD11B1 is linked to leiomyoma.