HSD11B1 and leiomyoma: Though further omics studies are needed to clarify how FKBP51-GR directly regulates intracellular HSD11β1 and alters the transcriptional activity in leiomyoma cells, we found that DEX treatment in the presence of FKBP5 induces HSD11B1 expression to a greater extent in leiomyoma cells compared to normal myometrium.