ADA and premenstrual tension: In accordance with this possible explanation, the following correlations are obtained: the erythrocyte total n-6 fatty acids and 22:4n-6 (ADA) correlated negatively with both EDSS and MSSS in the PMS group, and the correlations with MSSS remained significant after adjustment for age and BMI, thus linking lower levels of circulating n-6 with a more severe clinical phenotype of the PMS course.