The ways in which the ketogenic diet may be superior to other dietary interventions include better regulation of satiety and hunger, greater initial weight loss, favourable effect on glycaemic levels and fluctuations, favourable effect on insulin resistance, reduced inflammation, less need for obesity medication (as the effect of the diet itself is similar, but without the side effects), and positive psychological impact. Here, INS is linked to obesity due to melanocortin 4 receptor deficiency.