Cerebrospinal fluid (CSF) and plasma biomarkers related glial function, such as soluble triggering receptor expressed on myeloid cells 2 (sTREM2), chitinase‐3‐like protein 1 (YKL‐40) and glial fibrillary acidic protein (GFAP) have shown promise in reflecting neuroinflammation levels across different disease stages and correlating with core AD biomarkers.18, 19, 20, 21, 22, 23. Here, GFAP is linked to Alzheimer disease.