Further investigation into the heterogeneity of myeloid cells revealed that clusters C9, 11, and 13 exhibited elevated expression levels of myeloid‐derived suppressor cell (MDSC)‐associated genes, such as S100A8 and S10019, which have previously been utilized for defining MDSCs in cancer models[37, 38] (Figure S3A, Supporting Information). This evidence concerns the gene S100A8 and cancer.