In addition, serum reg1α levels correlated significantly with endoscopic inflammatory activity scores [MES in patients with UC (r = 0.489, p = 0.001) and SES-CD in patients with CD (r = 0.407, p = 0.001), both p < 0.001], suggesting that serum reg1α may be a potential serum biomarker for endoscopic activity in patients with IBD. The gene discussed is REG1A; the disease is inflammatory bowel disease.