RPSA and pancreatic neoplasm: reported that PRL29 could help with proliferation of pancreatic cancer cells.[37] Two cell experiment results indicated that RPSA served as a factor that regulate the migration of pancreatic cancer cells.[38, 39] However, another study found reduced RPSA immunohistochemical staining in pancreatic cancer compared to peripheral pancreatic tissue.[40] According the studies above, this cluster of proteins served as a regulator of pancreatic cancer cells.