In addition to 18F-FDG and 18F-NaF, newer PET tracers are under investigation for better imaging atherosclerosis, such as CXCR4-targeted 68 Ga-pentixafor, CCR2-targeted 64Cu-DOTA-ECL1i, and CCR5-targeted 64Cu-DOTA-DAPTA [37]. The gene discussed is CXCR4; the disease is atherosclerosis.