Significant decreases in mRNA levels of chemokines including Ccl2, Ccl7, Ccl20, Cxcl1, Cxcl3, Cxcl5, Csf1, Csf2, and Csf3, as well as collagens such as Col4a1, Col4a2, Col5a1, Col6a1, Col6a2, Col6a3, and Col8a1 were confirmed (Figure 3C–E), and the immunoblotting analysis also confirmed the reduction in COL5A1 protein levels (Figure S5A, Supporting Information), with consistent sequences observed in the TCGA‐pancreatic adenocarcinoma (PAAD) databases (Figure 3D,F). This evidence concerns the gene COL4A2 and pancreatic adenocarcinoma.