MAP1LC3B and Alzheimer disease: The results of the Spearman’s correlation test showed that the autophagosome (LC3B-II) levels in the cortex of male 3xTg-AD mice were negatively correlated with the NOP test (r = −1.000, P = 0.010; Fig. 7A), but positively correlated with the preference index of the novel object in the NOR test (r = 1.000, P = 0.010; Fig. 7B).