In this study, 37 tumors from MYCN non-amplified neuroblastoma patients were sequenced and the authors found two older children (NB1 and NB2) with advanced MYCN non-amplified neuroblastoma carried each one of the two following novel nonsense ATRX variants (p.Gln1670* or p.Glu1984*). The gene discussed is MYCN; the disease is neuroblastoma.