Noscapine (from phthalidisoquinoline group), an alkaloid derived from Papaver somniferum, selectively blocks well-established inflammatory transcription factors such as NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells), which plays a key role in the pathogenesis of several diseases, including Alzheimer’s disease, diabetes, colorectal cancer, and glioblastoma [83,183,194,195,196]. The gene discussed is NFKB1; the disease is glioblastoma.