Decreasing the viability of glioblastoma cells through TRPV1-independent mechanism:IC50 = 325.7 ± 12.4 μM at 24 h of treatmentIC50 = 265.7 ± 10.2 μM at 48 h of treatmentStimulating apoptosisInducing the expression of PPARγ in glioblastoma LN-18 cells by capsaicin in a dose-dependent mannerDecreasing collagen biosynthesis in glioblastoma cellsPotentiating the cytotoxicity of thiazolidinediones. The gene discussed is PPARG; the disease is glioblastoma.