As an example, apaQTL SNP rs8042489 was identified to colocalize with a NSCLC GWAS signal in the 15q25.1 loci (Figure S6A, Supporting Information), which was significantly associated with 3′UTR usage in TBC1D2B (Figure S6B, Supporting Information). The gene discussed is TBC1D2B; the disease is non-small cell lung carcinoma.