A variety of markers of muscle involvement has been investigated as potential prognostic biomarkers for ALS, including potassium,24, 25 creatine kinase,15, 24, 26 lactate dehydrogenase,24 myoglobin,15 troponin T,15, 27 AST, ALT,24 and creatinine.21, 25, 28, 29, 30. Here, MB is linked to amyotrophic lateral sclerosis.