For example, EGFR, a crucial receptor protein in stimulating both differentiation and proliferation of cancer cells, can be activated by its respective ligands,[32, 33] such as EGF and Decorin (DCN).[34] Notably, although EGFR exhibits seven glycopeptide variants, they all fall within a narrow range of Hm numbers, spanning from H5 to H8. This evidence concerns the gene EGF and cancer.