FUCA1 and colorectal carcinoma: N‐glycans synthesis is a multi‐compartmental process involving over 700 glycosyltransferases and glycosidases.[47] Our investigation identified aberrant levels of Tissue alpha‐L‐fucosidase (FUCA1) and ERO1‐like protein alpha (ERO1A), which showed the strongest correlations with dysregulated glycosylation scores in CRC, suggesting these enzymes may drive CRC progression.