However, adding NEUROD1 Exo‐mRNA to the dual DLL3 Exo‐mRNA/tEV‐mProtein biomarker slightly decreased the AUC/ROC: LS‐SCLC patients from 0.836 to 0.820, and ES‐SCLC patients from 0.839 to 0.811. This evidence concerns the gene DLL3 and small cell lung carcinoma.