ASCL1 and small cell lung carcinoma: By incorporating Exo‐ASCL1 and Exo‐POU2F3 mRNA expression with DLL3 Exo‐mRNA/tEV‐mProtein expression, the classifier enhances the AUC/ROC to 0.912 and 0.963 for limited‐ and extensive‐stage SCLC patients, respectively.