Skeletal muscle atrophy is a common pathological feature in a wide range of diseases, including aging, cancer‐associated cachexia, and diabetes.[37, 38, 39] In our study, we identified cytokines (IL1β, TNFα, and IL6) that suppress lncRNA‐MEG3 expression in cancer cell culture media, suggesting that dysregulated lncRNA‐MEG3 expression could contribute to muscle loss in these pathological conditions. This evidence concerns the gene IL6 and diabetes mellitus.