Given that acute pancreatitis‐associated adipose tissue has been found to undergo lipolysis even in the absence of adipocyte triglyceride lipase, and considering the recently reported important role of GREM1 in pancreatic cancer,17 we are particularly interested in exploring the relationship between hypertriglyceridemia‐induced pancreatitis and asparaginase‐induced pancreatitis. Here, DDHD2 is linked to acute pancreatitis.