Four weeks post infection with M.tb HN878, we observed a significant increase in circulating IFN-γ, TNF-α, IL-1β, IL-2, IL-6, IL-12p70, IL-17A/F, IL-15, and IL-33 levels in mice immunized with ID93+EmT4TM compared to saline controls. The gene discussed is IL15; the disease is infection.