PACSIN1 and hereditary hyperekplexia: Moreover, a startle disease‐associated missense variant in the motif, GlyR α1P366L (Figure 2) reduced the binding of GlyR α1 to syndapin I in peptide microarray assays (relative syndapin I binding to wild‐type and P366L 364–372 peptides: 0.4 versus 0.03).