CRTC1 and memory impairment: In addition, dysregulated CRTC1 in the hippocampus is known to contribute to Aβ oligomer‐induced memory impairment [49], and CRTC1 function is disrupted during memory formation in neurodegeneration [50], suggesting that CRTC1 can be regarded as a potential target to ameliorate aging‐generated episodic memory impairment.