Moreover, signaling mediated by Keratinocyte Growth Factor Receptor/Fibroblast Growth Factor Receptor 2b (KGFR/FGFR2b), an element related to the balanced maintenance of cellular differentiation and proliferation [60], was found to be suppressed due to the activity of the EGFR pathway which was increased by HPV18 E5 expression in cervical cancer [61]. The gene discussed is FGFR2; the disease is cervical carcinoma.