Conversely, inhibitors targeting caspase-9, pan-caspases, NLRP3 inflammasome, and RIPK1 significantly suppressed NF-κB activation, suggesting that these pathways are involved in the negative regulation of NF-κB activation during IBV infection, as previously suggested for other viral infections [56,57,58,59]. The gene discussed is NLRP3; the disease is viral infectious disease.