Of the 13 measured, 11 (GM-CSF, IFNγ, IL-1α, IL-1Β, IL-2, IL-4, IL-6, IL-10, IL-12, IL-18, and TNF-α) exhibited higher concentrations in the saliva of pigs with meningitis and S. suis infection. The gene discussed is IL4; the disease is infectious meningitis.